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WHO Classification of Tumours
Angiomyofibroblastoma
Connective, subcutaneous and other soft tissues


Definition

Angiomyofibroblastoma is an uncommon, benign soft tissue neoplasm usually arising in subcutaneous tissue in the pelviperineal region, in particular the vulva. It is histologically characterized by the presence of neoplastic spindle to round cells, dilated thin walled vessels, and stromal edema. The tumours are well circumscribed by a thin, fibrous pseudocapsule and generally measure <5cm in diameter
Click for details
Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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Angiomyofibroblastomas arise predominantly in women between menarche and menopause. Surgical excision is curative

Click for details
Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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