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WHO Classification of Tumours
Sebaceous adenoma


Sebaceous adenoma is a benign, well circumscribed neoplasm arising from the sebaceous glands. It usually presents as a small, yellowish, frequently crusted or scaly lesion in the sun exposed skin of head and neck. Sebaceous adenomas are typically solitary. Multiple lesions may indicate Muir-Torre syndrome . Histologically, the tumour is composed of lobular aggregates of fully differentiated sebocytes with a peripheral rim of basaloid cells. It is frequently connected to the overlying epidermis.
Sebaceous adenomas mainly arise in adults >40 years of age. The tumours are benign. In the context of Muir-Torre syndrome, the prognosis depends on the associated internal malignancies

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LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
3rd Edition
IARC Press: Lyon 2005