logo logo
Search: Organ site Search: Tumor / Syndrome
or
WHO Classification of Tumours
Plasma cell myeloma
Tumours of haematopoietic and lymphoid tissues


Definition

Plasma cell myeloma is a BM-based, multi­focal plasma cell neoplasm associated with an M-protein in serum and/or urine. In most cases there is disseminated BM involvement. The disease spans a clinical spectrum from asymptomatic to aggressive forms and disorders due to deposition of abnormal immunoglobulin chains in tissues
Click for details
Malpas J, Bergsagel D, Kyle R, Anderson K (Eds.)
Myeloma: Biology and Management
3rd Edition
Saumders: Philadelphia 2004



. The diagnosis is based on a combination of pathological, radiological and clinical features (Table 10.05).

> Variants
Three variants of plasma cell myeloma have been identified:
Asymptomatic (smoldering) myeloma
Non-secretory myeloma
Plasma cell leukaemia


> Related Topics
Definition: Plasma cell neoplasms
Introduction: Classification of lymphoid neoplasms