logo logo
Search: Organ site Search: Tumor / Syndrome
or
WHO Classification of Tumours
Periosteal osteosarcoma
Bone


Definition

Periosteal osteosarcoma is an intermediate grade chondroblastic osteosarcoma arising on the surface of bone. The tumour chiefly affects the diaphysis or diaphyseal-metaphyseal area of the long bones. Calcified spiculations perpendicular to the cortex give the tumour a sunburst appearance. The cartilaginous component predominates within the lesion. The cortex commonly appears thickened as a result of the production of a heavily ossified matrix, while the periphery tends to be uncalcified or only minimally calcified. The advancing margin is usually well demarcated by a capsule/pseudocapsule.
Periosteal osteosarcoma shows a peak incidence in the second and third decades of life, with slight male predominance. It is associated with a better prognosis than conventional osteosarcoma

Click for details
Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



.