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WHO Classification of Tumours


Osteochondroma is a common, benign cartilaginous neoplasm arising from the metaphysis of bone. It is histologically characterized by the presence of chondrocytes, a cartilage cap, and a fibrous perichondrium that extends to the periosteum of the bone. Irregular calcification is common. A thick and irregular cartilage cap (greater than 2cm) may be indicative of malignant transformation.
Most cases are diagnosed in the first three decades of life without sex predilection. Approximately 15% of osteochondroma patients have multiple lesions which are often asymptomatic. Surgical removal is usually curative. Recurrence in a well excised lesion may indicate malignancy

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Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002