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WHO Classification of Tumours
Lymphomatoid granulomatosis
Bronchus and lung


Lymphomatoid granulomatosis (LYG) is a rare extranodal neoplastic lymphoproliferative disease characterized by an angiocentric arrangement of tumor cells which is associated with angiodestruction. Tumour cells are Epstein-Barr virus (EBV)-positive B cells admixed with reactive T cells
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Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (Eds.)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
4th Edition
International Agency for Research on Cancer: Lyon 2008

Wester populations and males are more frequently affected and immunodeficiency is a risk factor. Predisposing conditions include allogeneic organ transplantation, Wiskott-Aldrich syndrome, human immunodeficiency virus (HIV) infection and X-linked lymphoproliferative syndrome .