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WHO Classification of Tumours
Solitary fibrous tumor
Liver and intrahepatic bile ducts


A relatively rare, spindle-cell, fibroblastic tumour that typically shows a prominent haemangiopericytoma-like vascular pattern. It is histopathologically characterized by the presence of round to spindle-shaped cells, hyalinized stroma formation, thin-walled branching blood vessels, and thin bands of collagen.

Hepatic solitary fibrous tumour (previously also known as localized fibrous tumour and localized fibrous mesothelioma) originates from the submesothelial tissue of the liver. It occurs in patients aged 1684 years (mean, 55 years)

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Moran CA, Ishak KG, Goodman ZD (1998)
Solitary fibrous tumor of the liver: a clinicopathologic and immunohistochemical study of nine cases.
Ann Diagn Pathol 2: 19-24

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Perini MV, Herman P, D'Albuquerque LA, Saad WA (2008)
Solitary fibrous tumor of the liver: report of a rare case and review of the literature.
Int J Surg 6: 396-9

and with a female-to-male predominance of 2 : 1. Clinical presentation includes mild abdominal discomfort and presence of a solid abdominal mass. Some cases are associated with hypoglycaemia caused by the production of an insulin-like growth factor
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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010