logo logo
Search: Organ site Search: Tumor / Syndrome
or
WHO Classification of Tumours
Leiomyoma, NOS
Stomach


Definition

Leiomyoma is a well-circumscribed benign smooth muscle neoplasm histologically characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.

Gastric intramural leiomyoma
This tumour is rare, approximately 50 times less common than gastrointestinal stromal tumor (GIST) . These tumours usually occur in older adults and clinically present similarly to GISTs. The tumours vary from minimal mural nodules to masses of >5cm in size. However, minimal leiomyomas have been commonly found in oesophagogastric resections for carcinoma

Click to access Pubmed
Abraham SC, Krasinskas AM, Hofstetter WL, Swisher SG, Wu TT (2007)
"Seedling" mesenchymal tumors (gastrointestinal stromal tumors and leiomyomas) are common incidental tumors of the esophagogastric junction.
Am J Surg Pathol 31: 1629-35



. Histologically, these tumours are composed of well-differentiated smooth-muscle cells with no or little atypia and mitotic activity, or isolated mitosis.
Smooth-muscle tumours with atypia and mitotic activity are designated leiomyosarcoma , and such tumours are distinctly rare in the stomach.