A common, malignant tumour characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreted product (e.g., mucinous, serous).
Those are malignant epithelial neoplasms accounting for 10% of all cancers world-wide. In all regions, the incidence of stomach cancer is declining but this cancer still represent a significant disease burden in areas with exposure to the main risk factors, Helicobacter pylori infection and high-salt diet. Elder people are preferentially affected. Clinical outcome depends of tumour grade and stage;for 2007, 5-year survival rates of 25%
Verdecchia A, Francisci S, Brenner H, Gatta G, Micheli A, Mangone L, Kunkler I, (2007)
have been reported .
Recent cancer survival in Europe: a 2000-02 period analysis of EUROCARE-4 data.
Lancet Oncol 8: 784-96
> Histological subtypes:
Poorly cohesive carcinoma, including signet ring cell carcinoma and other variants
Mixed cell adenocarcinoma