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Search: Organ site Search: Tumor / Syndrome
WHO Classification of Tumours
Rhabdomyosarcoma, NOS


A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites.

In the oesophagus, only a small number of well-documented rhabdomyosarcomas (of embryonal type) have been reported . These tumours have occurred in the distal oesophagus in older adults

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Vartio T, Nickels J, Höckerstedt K, Scheinin TM (1980)
Rhabdomyosarcoma of the oesophagus. Light and electron microscopic study of a rare tumor.
Virchows Arch A Pathol Anat Histol 386: 357-61

. Immunohistochemical demonstration of desmin and nuclear expression of myogenic regulatory proteins (MyoD1 or myogenin) is required for diagnosis.