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WHO Classification of Tumours
Squamous cell carcinoma, spindle cell
Esophagus


Definition

A poorly differentiated squamous cell carcinoma characterized by a variable presence of malignant cells with spindle cell features.
Click to access Pubmed
Lauwers GY, Grant LD, Scott GV, Carr NJ, Sobin LH (1998)
Spindle cell squamous carcinoma of the esophagus: analysis of ploidy and tumor proliferative activity in a series of 13 cases.
Hum Pathol 29: 863-8




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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010



. Grossly, it is polypoid, usually involving the middle and lower third of the oesophagus. Microscopically, it is biphasic with epithelial and spindle cells.