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WHO Classification of Tumours
Polymorphous low grade adenocarcinoma
Salivary glands


Definition

A low grade malignant epithelial neoplasm of the head and neck region, histologically characterized by uniform, small to medium size malignant epithelial cells with a variety of morphologic features that may be present within a tumor, including lobular, papillary, papillary-cystic, cribriform, and trabecular patterns.
Polymorphous low grade adenocarcinoma frequently arises in the oral cavity, with approximately 60% of the cases involving the palate. It usually has a favorable clinical outcome and a low metastatic potential

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Barnes L, Eveson JW, Reichart P, Sidransky D (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Head and Neck Tumours.
3rd Edition
IARC Press: Lyon 2005



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