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WHO Classification of Tumours
Undifferentiated carcinoma
Appendix


Definition

Undifferentiated carcinoma is a usually aggressive, malignant epithelial neoplasm composed of atypical cells which do not display evidence of glandular, squamous, or urothelial cell differentiation.

Undifferentiated carcinomas occur in the appendix but are rare. Their histology corresponds to that of undifferentiated carcinomas of the colorectum.