A common, malignant tumour characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreted product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell adenocarcinoma, hepatocellular carcinoma, colon adenocarcinoma, and prostate adenocarcinoma.
This is a malignant epithelial neoplasm with invasion beyond the muscularis mucosae. It occurs in 0.1–0.2% of appendicectomies, corresponding to an estimated incidence of 0.2 per 100 000 per year. The causes are unclear, however there is an association with neoplasia elsewhere in the large intestine and a preexisting chronic ulcerative colitis may be a risk factor. Elder people are preferentially affected. Clinical outcome depends of tumour grade, stage and histological type, e.g.mucinous versus non-mucinous
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> Histological subtypes
Low-grade appendiceal mucinous neoplasm (LAMN)
Signet ring cell carcinoma