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WHO Classification of Tumours
Hibernoma
Connective, subcutaneous and other soft tissues


Definition

Hibernoma is a rare, benign slow-growing adipose tissue tumour, histologically characterized by the presence of polygonal brown fat cells with multivacuolated and/or granular cytoplasm admixed with white adipose tissue.
Hibernomas arise in the subcutis; they most commonly affect the thigh, followed by the trunk, upper extremity, and head and neck. Many lesions originate at the sites where brown fat is normally found in hibernating animals and human newborns. The tumours are lobular and well demarcated; sizes range from 1 to 24 cm

Click for details
Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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Hibernoma affects predominantly young adults (mean age, 38 years), with a slight predilection for males. The tumour is usually painless and complete local excision is curative

Click for details
Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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