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WHO Classification of Tumours
Granular cell tumor of the sellar region
Pituitary gland


Granular cell tumor of the sellar region is a generally benign intra- or suprasellar mass arising from the neurohypophysis or infundibulum. It is composed of nests of large cells with granular, eosinophilic cytoplasm due to abundant intracytoplasmic lysosomes.

It generally has a slow progression and lacks invasive growth. Surgical removal is the preferred therapy for larger tumours

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Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (Eds.)
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007