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WHO Classification of Tumours
Acinar cell cystadenoma
Pancreas


Signs and Symptoms

Cases are divided into two categories:

1) Clinically recognized macroscopic lesions
They may present with abdominal pain or, in one case, polyarthralgia, or they may be detected by radiographic imaging in asymptomatic patients

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Zamboni G, Terris B, Scarpa A, Kosmahl M, Capelli P, Klimstra DS, Lam PW, Klöppel G (2002)
Acinar cell cystadenoma of the pancreas: a new entity?
Am J Surg Pathol 26: 698-704



. They range from 1.5 to 10.0 cm in diameter (mean, 6 cm) and form unilocular or multilocular cystic masses that are usually grossly circumscribed
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Albores-Saavedra J (2002)
Acinar cystadenoma of the pancreas: a previously undescribed tumor.
Ann Diagn Pathol 6: 113-5




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Chatelain D, Paye F, Mourra N, Scoazec JY, Baudrimont M, Parc R, Flejou JF (2002)
Unilocular acinar cell cystadenoma of the pancreas an unusual acinar cell tumor.
Am J Clin Pathol 118: 211-4




Click to access Pubmed
Zamboni G, Terris B, Scarpa A, Kosmahl M, Capelli P, Klimstra DS, Lam PW, Klöppel G (2002)
Acinar cell cystadenoma of the pancreas: a new entity?
Am J Surg Pathol 26: 698-704



. Individual cysts range from 1 mm to several cm. The cysts contain watery fluid and have a smooth lining. Communication with the ductal system of the pancreas is rare. Some cases are multicentric and others diffusely involve the entire gland, with islands of parenchyma between the cysts.

2) Incidental microscopic lesions
Incidentally detected acinar cell cystadenomas are identified only microscopically in pancreata removed for other reasons. They are usually < 1.0 cm and unilocular, and some are not apparent grossly

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Bosman FT, Carneiro F, Hruban RH, Theise ND (Eds.)
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010



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