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WHO Classification of Tumours
Anaplastic astrocytoma
Tumours of the central nervous system


Macroscopy

Frequently, it is not possible to grossly distinguish between a low-grade and an anaplastic astrocytoma. On a cut surface, the higher cellularity of the anaplastic astrocytoma produces a discernible tumour mass with sometimes more clear distinction from surrounding brain structures than seen in low-grade diffuse astrocytomas. As in the latter, there is a tendency to infiltrate without frank tissue destruction. This often leads to a marked enlargement of invaded structures, e.g. adjacent gyri and basal ganglia. Macroscopic cysts are uncommon, but frequently there are areas of granularity, opacity and a softer consistency.


Temporal location
Temporal location
Infiltration of midline structures
Infiltration of midline structures
Malignant brainstem glioma
Malignant brainstem glioma