Tumours of the central nervous system
Frequently, it is not possible to grossly distinguish between a low-grade and an anaplastic astrocytoma. On a cut surface, the higher cellularity of the anaplastic astrocytoma produces a discernible tumour mass with sometimes more clear distinction from surrounding brain structures than seen in low-grade diffuse astrocytomas. As in the latter, there is a tendency to infiltrate without frank tissue destruction. This often leads to a marked enlargement of invaded structures, e.g. adjacent gyri and basal ganglia. Macroscopic cysts are uncommon, but frequently there are areas of granularity, opacity and a softer consistency.
|Infiltration of midline structures|
|Malignant brainstem glioma|